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Retina Implant AG. Retina Implant AG is a medical technology company. The Company is developing a retinal prosthesis for blind patients to gain back lost sight. SECTOR. Technology. INDUSTRY. Retina Implant AG is the leading developer of subretinal implants for partially sighted and blind patients. After extensive research with German university hospitals and institutes which began with a large grant from the German Federal Ministry of Research and Education in , Retina Implant AG was founded by Dr. Eberhart Zrenner and his colleagues in with private investors with the. Retina Implant AG is located in Reutlingen, Baden-Württemberg, Germany and is part of the Photographic & Optical Equipment/Supplies Manufacturing Industry. Retina Implant AG has 22 employees at this location and generates $ million in sales (USD). (Sales figure is estimated). There are 2 companies in the Retina Implant AG corporate creacora.deees: Retina Implant AG, Reutlingen, Germany, District Court of Stuttgart HRB Public funding, Earnings, Revenue, Employees, Network, Financial information.
Following 12 years of successful development at Retina Implant AG, Dr. Wrobel , CEO of the company, has announced his resignation by mutual consent. The resignation will take effect on September 30, Wrobel’s departure, along with recent CE-approval of the new RETINA IMPLANT Alpha AMS, indicates a new era for the company; one that will be heavily influenced by navigating the challenges of distribution. Wrobel said of his departure: „This is the right time for me to hand over operational responsibility.
It has been a very thrilling and satisfying time. I hope that Retina implant AG has as much success in the future as they have now. The supervisory board expressed their thanks to Dr. Wrobel for his exceptional and treasured contribution to the company’s success. The chairman, Prof.
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Download PDF. In the United States, approximately , people have retinitis pigmentosa RP , and the number worldwide is estimated at 1. Although a nutritional regimen has shown promise in delaying RP progression, 2 there is yet no treatment that can undo the sight-robbing damage once it has occurred. But patients received more than a glimmer of hope with the February FDA approval of the Argus II Retinal Prosthesis System Second Sight Medical Products for use in advanced RP.
It received the European CE mark in The Argus II is an epiretinal-stimulating device designed to improve visual functioning in people who are blind—or, more accurately, to give people who are blind from severe RP the ability to perceive black and white images and motion. Although it is currently the only such device approved in the United States, others are pressing forward in development, most notably the Alpha IMS, manufactured by Retina Implant AG in Germany.
Now that this critical approval barrier has been crossed, what are the implications for RP patients and their ophthalmologists? Three retina specialists take a look at where we are now—and what impediments remain—in the development and adoption of retinal prostheses. This type of approval does not require proof of effectiveness; rather, Second Sight had to provide evidence to the FDA showing that the probable benefits of Argus II outweigh its risks and that no comparable device is available for treating RP.
Now, Argus II can be offered to all RP patients who meet the treatment criteria, not just those in clinical trials. According to product labeling, patients must be at least 25 years old, with a diagnosis of retinitis pigmentosa, with bare light or no light perception in both eyes, and a history of previous useful form vision.
Moreover, they must be phakic or pseudophakic as well as willing and able to receive the recommended postimplant clinical follow-up, device fitting, and visual rehabilitation. A long process of development.
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Effective date : Free format text : PATENTED CASE. Owner name : RETINA IMPLANT GMBH, GERMANY. Year of fee payment : 4. Owner name : RETINA IMPLANT AG, GERMANY. Year of fee payment : 8. Year of fee payment : A retina implant, comprises a surface and a plurality of pixel elements disposed on the surface for receiving and converting incoming light energy into electric energy.
At least one amplifier is provided in the implant, and a plurality of stimulation electrodes supplied via the at least one amplifier as a function of signals received by the pixel elements. At least one light-sensitive reference element is coupled with the at least one amplifier for controlling amplification thereof as a function of light energy impinging on the at least one reference element.
The invention is related to a retina implant, comprising a surface with a plurality of pixel elements disposed thereon for receiving and converting incoming light energy into electric energy, at least one amplifier and a plurality of stimulation electrodes being supplied via the at least one amplifier as a function of the signals received by the pixel elements. A retina implant of the afore-specified kind is disclosed in U.
This prior art retina implant is a so-called epiretinal implant which is placed onto the surface of the retina. Essentially it consists of a chip with a plurality of light-sensitive elements being provided on a surface thereof facing the lens of the eye, and converting the image projected through the lens into corresponding electric signals which shall stimulate the photoreceptors disposed in the retina.
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Retinal prostheses for restoration of sight to patients blinded by retinal degeneration are being developed by a number of private companies and research institutions worldwide. The system is meant to partially restore useful vision to people who have lost their photoreceptors due to retinal diseases such as retinitis pigmentosa RP or age-related macular degeneration AMD. Three types of retinal implants are currently in clinical trials: epiretinal on the retina , subretinal behind the retina , and suprachoroidal between the choroid and the sclera.
Retinal implants introduce visual information into the retina by electrically stimulating the surviving retinal neurons. So far, elicited percepts had rather low resolution, and may be suitable for light perception and recognition of simple objects. Foerster was the first to discover that electrical stimulation of the occipital cortex could be used to create visual percepts, phosphenes.
The first application of an implantable stimulator for vision restoration was developed by Drs. Brindley and Lewin in This experiment demonstrated the viability of creating visual percepts using direct electrical stimulation, and it motivated the development of several other implantable devices for stimulation of the visual pathway, including retinal implants. Retinal stimulation devices, in particular, have become a focus of research as approximately half of all cases of blindness are caused by retinal damage.
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Life Sciences Pharmaceuticals Therapeutic Area Ophthalmology. Implantable Miniature Telescope, one of the segments analyzed in the report, is projected to record a 9. After an early analysis of the business implications of the pandemic and its induced economic crisis, growth in the Argus II segment is readjusted to a revised 9. The U. Among the other noteworthy geographic markets are Japan and Canada, each forecast to grow at 8. Within Europe, Germany is forecast to grow at approximately 7.
Retina Implant Alpha AMS Segment to Record 8. China will remain among the fastest growing in this cluster of regional markets. Select Competitors Total 40 Featured – Abbott Vascular Bionic Eye Technologies, Inc. Bionic Vision Australia Drager Medical GmbH Labtician Ophthalmics, Inc. Nano Retina Philips Healthcare Pixium Vision SA Retina Implant AG Second Sight Medical Products Inc. VisionCare, Inc.
Visus Technology, Inc.
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Retinal prostheses, a type of bionic eye, are implantable electronic devices designed to stimulate sensation of vision in the eyes of individuals with significant retinal diseases such as retinitis pigmentosa or age-related macular degeneration, where the optic nerve and visual cortex are unaffected. In the normal eye, photoreceptors located within the outer layers of the retina contain light-sensitive pigment that trigger the phototransduction cascade to generate neuronal signals in the presence of light stimuli.
These signals are passed to and processed by a complex network of neurons within the middle layers of the retina before reaching the retinal ganglion cells RGC within the inner layers. Axonal processes from RGCs ultimately form the optic nerve to transmit the light-evoked neuronal signals to the visual cortex. In congenital retinal dystrophies such as retinitis pigmentosa, the outer layers of the retina where photoreceptors reside are gradually lost, thereby causing progressive visual loss.
However, inner retinal layers including RGCs are partially spared. The first concept of electrical stimulation evoking visual perception or „phosphones“ was by Charles Le Roy in when he observed that electrical current applied across the ocular surface of a blind patient resulted in subjective perception of flashes of light. In , the first known proposal for a retinal prosthesis type device was outlined by Tassicker in Melbourne, Australia.
Although visual prostheses may conceivably be developed for any part of the visual pathway including the visual cortex itself, the retina is considered to be the easiest target for treating outer retinal disease due to its easy access and partially intact geospatial neuronal architecture and processing units. Designs for retinal prostheses are generally categorized based on where in the eye the device is intended to be placed and how the device delivers electrical impulses to RGCs.
Most devices are placed either epiretinally, on the retina surface and adjoining the RGC layer, or subretinally, outside of the retina adjoining or in place of the remnants of the retinal pigmented epithelial and photoreceptor layers. Epiretinal designs benefit from being easier and less risky to implant while subretinal designs may benefit by utilizing intact middle retinal layer processing pathways formed by amacrine, horizontal, and bipolar cells.
Electrical impulse delivery is accomplished by either micro-photodiode arrays or micro-electrode arrays. The former utilizes an array of tiny photodiodes to generate electrical current from light entering the eye while the latter depends on a camera, processing unit, and a transformer to convert the light from images to corresponding geographical impulses generated by an array of micro-electrodes.
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Retina Implant AG: Safety & Efficacy of Subretinal Implants for Partial Restoration of Vision in Blind Patients: A Prospective Mono- & Multicenter Clinical Study Based on Randomized Intra-individual Implant Activation in Degenerative Retinal Disease Patients. Retinal Degeneration Retinitis Pigmentosa: Retina Implant AG. Retina Implant AG, the leading developer of subretinal implants for patients blinded by retinitis pigmentosa (RP), today announced that its wireless subretinal implant technology, the Alpha IMS, has received CE Mark. Retina Implant’s technology, which has been in clinical trials across the world since , is designed to restore useful vision in.
Retinitis pigmentosa RP is a degenerative eye disease that affects , people in the United States and Europe and has left 15 million people permanently blind worldwide. German biotechnology firm Retina Implant AG has developed a microchip that provides a useful degree of artificial vision in patients who have been blind for even long periods.
After successful clinical trials in Germany, the chip is now being tested in Hong Kong and Britain before moving on to planned trials in the U. RP is a disease that mainly affects the retina — specifically, the photoreceptors in the macular layer. These receptors slowly degrade until the patient ends up blind. Though the disease is incurable, one bright spot is that the nerves of the retina remain functional.
If these nerves can be stimulated, then some form of vision might be recovered. The device is a light-sensitive, externally powered microchip. This is surgically implanted beneath the transparent top membrane of the retina and into the macular region. This is the area of the eye where clear images are formed in normal-sighted individuals and where the implant is best protected against working loose.